Al-Kafrayn was located in an open landscape of gentle slopes and shallow wadis. It was built on a hilltop surrounded by wadis that separated long, sloping hills, about 6 km north of Wadi Ara. A secondary road led northwest to the Haifa-Jenin highway (which bordered on Marj ibn Amir). Al-Kafrayn, which means 'the two villages' in Arabic, was called Caforana by the Crusaders. In the late nineteenth century, al-Kafrayn had 200 residents who cultivated 30 faddans (1
Zionist forces claimed to have occupied the village on 12 April 1948, and Arab Liberation Army (ALA) records indicate that Arab forces withdrew from an area just west of al-Kafrayn the following day. The Palmach attack on al-Kafrayn was part of an operation launched after the battle of Mishmar ha-Emeq. When Jewish Agency Chairman David Ben-Gurion and the Haganah command rejected the ALA's offer of a ceasefire in that battle, they also decided to attack and destroy about ten villages near the settlement, including al-Kafrayn, which, acording to the New York Times, was the largest. A 12 April Haganah broadcast was quoted by the New York Times as saying that it was the fifth village around Mishmar ha-Emeq to be occupied by their forces.
Israeli historian Benny Morris reports that the village was partially destroyed during its occupation, but final demolition was postponed for a week, due to the Palmach's plan to use the village to train units to fight in built-up areas. On 19 April the Haganah General Staff was informed: 'Yesterday company exercises in fighting in built-up areas took place south and east of Mishmar Ha'emek. At the end of the exercises, the village of el Kafrin was blown up completely.'
No Israeli settlements are on village lands, but some of these lands are occupied by a military training camp.
The site and its surrounding area are divided between a military training camp and a cow pasture. A rubble-filled area has been fenced in and is covered with dirt, underbrush, and thorns. Almond, olive, and fig trees are scattered around the site.